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BACH1
Transcriptional regulator that acts as repressor or activator, depending on the context. Binds to NF-E2 DNA binding sites. Play important roles in coordinating transcription activation and repression by MAFK. Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway. Belongs to the bZIP family. CNC subfamily. Note: This description may include information from UniProtKB.
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| Protein type: DNA-binding; Transcription factor |
| Chromosomal Location of mouse Ortholog: 16|16 C3.3 |
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Cellular Component:
nucleus; RNA polymerase II transcription regulator complex
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Molecular Function:
DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding
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Biological Process:
DNA repair; negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; regulation of DNA-templated transcription; regulation of transcription by RNA polymerase II; regulation of transcription involved in G1/S transition of mitotic cell cycle; regulation of transcription involved in G2/M transition of mitotic cell cycle
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Reference #:
P97302
(UniProtKB)
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Alt. Names/Synonyms: 6230421P05Rik; AI323795; Bach1; BTB and CNC homolog 1; BTB and CNC homology 1; BTB and CNC homology 1 transcription factor; BTB and CNC homology 1, basic leucine zipper transcription factor 1; Transcription regulator protein BACH1
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Gene Symbols: Bach1
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Molecular weight:
81,374 Da
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Basal Isoelectric point:
4.91
Predict pI for various phosphorylation states
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