EPB41L1 iso5
May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Adaptor/scaffold |
Chromosomal Location of mouse Ortholog: 2 H1|2 77.39 cM |
Cellular Component:
cytoplasm; cytoskeleton; cytosol; plasma membrane; postsynaptic density; protein-containing complex; synaptic membrane
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Molecular Function:
actin binding; cytoskeletal protein binding; protein binding; signaling receptor binding; structural molecule activity
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Biological Process:
actomyosin structure organization; cortical actin cytoskeleton organization
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Reference #:
A2AUK5
(UniProtKB)
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Alt. Names/Synonyms: 4.1; 4.1N; Band 4.1-like protein 1; Epb4.1; Epb4.1l1; Epb41l1; EPB41L1 iso5; erythrocyte membrane protein band 4.1 like 1; erythrocyte protein band 4.1 like 1; erythrocyte protein band 4.1-like 1; mKIAA0338; NBL1; neuronal protein 4.1; OTTMUSP00000016920; OTTMUSP00000016923; OTTMUSP00000017082
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Gene Symbols: Epb4.1l1
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Molecular weight:
98,315 Da
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Basal Isoelectric point:
5.46
Predict pI for various phosphorylation states
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