ARHGAP5 iso3 GTPase-activating protein for Rho family members. Detected in skin fibroblasts (at protein level) (PubMed:8537347). 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rac/Rho; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 12 C1|12 22.16 cM
Cellular Component:  cytoplasm; cytosol; endoplasmic reticulum; membrane; plasma membrane
Molecular Function:  GTP binding; GTPase activator activity; GTPase activity; SH2 domain binding
Biological Process:  mammary gland development; positive regulation of cell migration; positive regulation of mesenchymal cell proliferation; regulation of cell size; signal transduction
Reference #:  E9PYT0 (UniProtKB)
Alt. Names/Synonyms: Arhgap5; ARHGAP5 iso3; p190; p190-; p190-B; p190B; Rho GTPase activating protein 5; Rho GTPase-activating protein 5; rho-type GTPase-activating protein 5
Gene Symbols: Arhgap5
Molecular weight: 172,472 Da
Basal Isoelectric point: 6.11  Predict pI for various phosphorylation states
CST Pathways:  Adherens Junction Dynamics
Select Structure to View Below

ARHGAP5 iso3

Protein Structure Not Found.


Cross-references to other databases:  Pfam  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein