TAF9B
Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription. Belongs to the TAF9 family. Note: This description may include information from UniProtKB.
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Protein type: DNA-binding |
Chromosomal Location of human Ortholog: Xq21.1 |
Cellular Component:
nucleoplasm; transcription factor TFIID complex; transcription factor TFTC complex
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Molecular Function:
protein binding; protein heterodimerization activity; RNA polymerase II general transcription initiation factor activity; transcription corepressor activity
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Biological Process:
DNA-templated transcription initiation; negative regulation of apoptotic process; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of transcription by RNA polymerase II; positive regulation of cell growth; protein stabilization; transcription by RNA polymerase II
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Reference #:
Q9HBM6
(UniProtKB)
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Alt. Names/Synonyms: DN-7; DN7; Neuronal cell death-related protein 7; TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa; TAF9B; TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa; TAF9L; TAFII31L; TATA-box binding protein associated factor 9b; TBP-associated factor 9L; TFIID-31; transcription associated factor TAFII31L; transcription initiation factor IID, 31kD subunit; Transcription initiation factor TFIID subunit 9-like; Transcription initiation factor TFIID subunit 9B; Transcription-associated factor TAFII31L
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Gene Symbols: TAF9B
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Molecular weight:
27,622 Da
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Basal Isoelectric point:
9.58
Predict pI for various phosphorylation states
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CST Pathways:
Protein Acetylation
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