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ZAP3
Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation. Expressed in neuronal, neuroblastoma and embryonic kidney cell lines (at protein level). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Transcription factor |
| Chromosomal Location of human Ortholog: 14q24.3 |
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Cellular Component:
cytosol; nuclear speck; nucleoplasm; nucleus
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Molecular Function:
protein binding
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Reference #:
P49750
(UniProtKB)
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Alt. Names/Synonyms: C14orf170; nuclear protein ZAP; Nuclear protein ZAP3; PPP1R169; protein phosphatase 1, regulatory subunit 169; YLP motif containing 1; YLP motif-containing protein 1; YLPM1; ZAP; ZAP113; ZAP3
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Gene Symbols: YLPM1
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Molecular weight:
241,645 Da
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Basal Isoelectric point:
6.12
Predict pI for various phosphorylation states
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