ZAP3 Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation. Expressed in neuronal, neuroblastoma and embryonic kidney cell lines (at protein level). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Chromosomal Location of human Ortholog: 14q24.3
Cellular Component:  cytosol; nuclear speck; nucleoplasm; nucleus
Molecular Function:  protein binding
Reference #:  P49750 (UniProtKB)
Alt. Names/Synonyms: C14orf170; nuclear protein ZAP; Nuclear protein ZAP3; PPP1R169; protein phosphatase 1, regulatory subunit 169; YLP motif containing 1; YLP motif-containing protein 1; YLPM1; ZAP; ZAP113; ZAP3
Gene Symbols: YLPM1
Molecular weight: 241,645 Da
Basal Isoelectric point: 6.12  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene