RBM7 Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters. Possible involved in germ cell RNA processing and meiosis. Ubiquitous. Note: This description may include information from UniProtKB.
Protein type: RNA-binding
Chromosomal Location of human Ortholog: 11q23.2
Cellular Component:  nucleoplasm; nucleus
Molecular Function:  protein binding
Biological Process:  meiotic cell cycle
Reference #:  Q9Y580 (UniProtKB)
Alt. Names/Synonyms: FLJ11153; RBM7; RNA binding motif protein 7; RNA-binding motif protein 7; RNA-binding protein 7
Gene Symbols: RBM7
Molecular weight: 30,504 Da
Basal Isoelectric point: 9.56  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene