talin 2 As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 15q22.2
Cellular Component:  actin cytoskeleton; cytoplasm; plasma membrane; ruffle; synapse
Molecular Function:  actin binding; actin filament binding; protein binding; structural constituent of cytoskeleton; structural molecule activity
Biological Process:  cell adhesion; cell-cell junction assembly; cytoskeletal anchoring at plasma membrane
Reference #:  Q9Y4G6 (UniProtKB)
Alt. Names/Synonyms: DKFZp451B1011; DKFZp686I0976; DKFZp686K0979; ILWEQ; KIAA0320; talin 2; Talin-2; TLN2
Gene Symbols: TLN2
Molecular weight: 271,613 Da
Basal Isoelectric point: 5.4  Predict pI for various phosphorylation states
Select Structure to View Below

talin 2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB