DDX41 Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing. Belongs to the DEAD box helicase family. DDX41 subfamily. Note: This description may include information from UniProtKB.
Protein type: EC; Helicase; RNA splicing; RNA-binding; Spliceosome
Chromosomal Location of human Ortholog: 5q35.3
Cellular Component:  catalytic step 2 spliceosome; cytosol; nucleus; spliceosomal complex
Molecular Function:  ATP binding; ATP hydrolysis activity; metal ion binding; protein binding; RNA binding; RNA helicase activity
Biological Process:  apoptotic process; cell differentiation; cell population proliferation; mRNA splicing, via spliceosome
Disease: Myeloproliferative/lymphoproliferative Neoplasms, Familial (multiple Types), Susceptibility To
Reference #:  Q9UJV9 (UniProtKB)
Alt. Names/Synonyms: 2900024F02Rik; ABS; DDX41; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; DEAD box protein 41; DEAD box protein abstrakt homolog; DEAD-box helicase 41; DEAD-box protein abstrakt; MGC8828; MPLPF; Probable ATP-dependent RNA helicase DDX41; putative RNA helicase
Gene Symbols: DDX41
Molecular weight: 69,838 Da
Basal Isoelectric point: 6.4  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene