cytohesin 4 Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP. Expressed predominantly in peripheral blood leukocytes. Note: This description may include information from UniProtKB.
Protein type: GEF; GEF, ARF
Chromosomal Location of human Ortholog: 22q13.1
Cellular Component:  centriolar satellite; cytosol; Golgi membrane; intercellular bridge; plasma membrane
Molecular Function:  guanyl-nucleotide exchange factor activity; lipid binding; protein binding
Biological Process:  regulation of ARF protein signal transduction; regulation of catalytic activity
Reference #:  Q9UIA0 (UniProtKB)
Alt. Names/Synonyms: CYH4; CYT4; CYTH4; cytohesin 4; Cytohesin-4; DJ63G5.1; PH, SEC7 and coiled-coil domain-containing protein 4; pleckstrin homology, Sec7 and coiled-coil domains 4; pleckstrin homology, Sec7 and coiled/coil domains 4; PSCD4
Gene Symbols: CYTH4
Molecular weight: 45,672 Da
Basal Isoelectric point: 6.08  Predict pI for various phosphorylation states
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cytohesin 4

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB