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cytohesin 4
Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP. Expressed predominantly in peripheral blood leukocytes. Note: This description may include information from UniProtKB.
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| Protein type: GEF; GEF, ARF |
| Chromosomal Location of human Ortholog: 22q13.1 |
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Cellular Component:
centriolar satellite; cytosol; Golgi membrane; intercellular bridge; plasma membrane
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Molecular Function:
guanyl-nucleotide exchange factor activity; lipid binding; protein binding
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Biological Process:
regulation of ARF protein signal transduction; regulation of catalytic activity
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Reference #:
Q9UIA0
(UniProtKB)
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Alt. Names/Synonyms: CYH4; CYT4; CYTH4; cytohesin 4; Cytohesin-4; DJ63G5.1; PH, SEC7 and coiled-coil domain-containing protein 4; pleckstrin homology, Sec7 and coiled-coil domains 4; pleckstrin homology, Sec7 and coiled/coil domains 4; PSCD4
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Gene Symbols: CYTH4
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Molecular weight:
45,672 Da
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Basal Isoelectric point:
6.08
Predict pI for various phosphorylation states
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