NUCKS Widely expressed, with highest levels in thyroid gland, prostate and uterus and in fetal liver, thymus and lung. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component:  chromatin; cytoplasm; nuclear chromatin; nucleolus; nucleus
Molecular Function:  chromatin binding; DNA-binding transcription activator activity, RNA polymerase II-specific; double-stranded DNA binding; single-stranded DNA binding; transcription factor binding
Biological Process:  cellular glucose homeostasis; cellular response to X-ray; chromatin organization; double-strand break repair via homologous recombination; gene conversion; interstrand cross-link repair; modulation by host of RNA binding by virus; modulation by host of viral RNA-binding transcription factor activity; positive regulation by host of viral genome replication; positive regulation by host of viral transcription; positive regulation of insulin receptor signaling pathway; positive regulation of transcription by RNA polymerase II; regulation of DNA replication; regulation of DNA strand elongation; regulation of insulin receptor signaling pathway; regulation of transcription by RNA polymerase II; release from viral latency; replication fork processing
Reference #:  Q9H1E3 (UniProtKB)
Alt. Names/Synonyms: FLJ21480; FLJ32016; FLJ38536; JC7; NUCKS; NUCKS1; nuclear casein kinase and cyclin dependent kinase substrate 1; nuclear casein kinase and cyclin-dependent kinase substrate 1; Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1; Nuclear ubiquitous casein and cyclin-dependent kinases substrate; nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate; P1; potential LAG1 interactor
Gene Symbols: NUCKS1
Molecular weight: 27,296 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
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NUCKS

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene