WDR33 Essential for both cleavage and polyadenylation of pre-mRNA 3' ends. Belongs to the WD repeat WDR33 family. Most highly expressed in testis. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of human Ortholog: 2q14.3
Cellular Component:  collagen trimer; fibrillar center; mRNA cleavage and polyadenylation specificity factor complex; nucleoplasm; nucleus
Biological Process:  mRNA polyadenylation; postreplication repair; spermatogenesis
Reference #:  Q9C0J8 (UniProtKB)
Alt. Names/Synonyms: FLJ11294; NET14; pre-mRNA 3' end processing protein WDR33; WD repeat domain 33; WD repeat-containing protein 33; WD repeat-containing protein of 146 kDa; WD repeat-containing protein WDC146; WDC146; WDR33
Gene Symbols: WDR33
Molecular weight: 145,891 Da
Basal Isoelectric point: 9.24  Predict pI for various phosphorylation states
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WDR33

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein