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WDR33
Essential for both cleavage and polyadenylation of pre-mRNA 3' ends. Belongs to the WD repeat WDR33 family. Most highly expressed in testis. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Adaptor/scaffold |
| Chromosomal Location of human Ortholog: 2q14.3 |
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Cellular Component:
collagen trimer; fibrillar center; mRNA cleavage and polyadenylation specificity factor complex; nucleoplasm; nucleus
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Biological Process:
mRNA polyadenylation; postreplication repair; spermatogenesis
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Reference #:
Q9C0J8
(UniProtKB)
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Alt. Names/Synonyms: FLJ11294; NET14; pre-mRNA 3' end processing protein WDR33; WD repeat domain 33; WD repeat-containing protein 33; WD repeat-containing protein of 146 kDa; WD repeat-containing protein WDC146; WDC146; WDR33
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Gene Symbols: WDR33
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Molecular weight:
145,891 Da
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Basal Isoelectric point:
9.24
Predict pI for various phosphorylation states
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