DATF1
Putative transcription factor, weakly pro-apoptotic when overexpressed. Tumor suppressor. Required for early embryonic stem cell development. Isoform 2: Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes. Ubiquitous. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Transcription factor |
Chromosomal Location of human Ortholog: 20q13.33 |
Cellular Component:
cytoplasm; nucleus; spindle
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Molecular Function:
metal ion binding
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Biological Process:
apoptotic signaling pathway; DNA-templated transcription
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Reference #:
Q9BTC0
(UniProtKB)
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Alt. Names/Synonyms: BYE1; C20orf158; DATF-1; DATF1; death associated transcription factor 1; death inducer-obliterator 1; Death-associated transcription factor 1; Death-inducer obliterator 1; DIDO1; DIDO2; DIDO3; DIO-1; DIO1; dJ885L7.8; DKFZp434P1115; FLJ11265; hDido1; KIAA0333; MGC16140
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Gene Symbols: DIDO1
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Molecular weight:
243,873 Da
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Basal Isoelectric point:
8.09
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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