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Sec5
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. Widely expressed with highest levels in brain and placenta. Note: This description may include information from UniProtKB.
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| Protein type: Vesicle |
| Chromosomal Location of human Ortholog: 6p25.3 |
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Cellular Component:
cytosol; exocyst; Flemming body; plasma membrane
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Molecular Function:
protein binding; protein kinase binding; small GTPase binding
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Biological Process:
exocytosis; Golgi to plasma membrane transport; membrane fission; mitotic cytokinesis; protein transport; regulation of entry of bacterium into host cell; vesicle docking involved in exocytosis; vesicle tethering involved in exocytosis
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Disease: Neurodevelopmental Disorder With Dysmorphic Facies And Cerebellar Hypoplasia
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Reference #:
Q96KP1
(UniProtKB)
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Alt. Names/Synonyms: EXOC2; Exocyst complex component 2; Exocyst complex component Sec5; FLJ11026; SEC5; Sec5 protein; SEC5-like 1; SEC5L1; Sec5p
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Gene Symbols: EXOC2
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Molecular weight:
104,066 Da
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Basal Isoelectric point:
6.46
Predict pI for various phosphorylation states
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