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S100A16
Calcium-binding protein. Binds one calcium ion per monomer. Can promote differentiation of adipocytes (in vitro). Overexpression in preadipocytes increases their proliferation, enhances adipogenesis and reduces insulin-stimulated glucose uptake. Belongs to the S-100 family. Ubiquitous (PubMed:14684152). Highly expressed in esophagus, adipose tissues and colon. Expressed at lower level in lung, brain, pancreas and skeletal muscle. Expression is up-regulated in tumors of bladder, lung, thyroid gland, pancreas and ovary (PubMed:14684152). Expressed in astrocytes (PubMed:17030513). Note: This description may include information from UniProtKB.
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| Protein type: Nucleolus |
| Chromosomal Location of human Ortholog: 1q21.3 |
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Cellular Component:
cytosol; extracellular space; nucleolus; nucleus; perinuclear region of cytoplasm; plasma membrane
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Molecular Function:
calcium ion binding; calcium-dependent protein binding; protein binding; protein homodimerization activity
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Biological Process:
response to calcium ion
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Reference #:
Q96FQ6
(UniProtKB)
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Alt. Names/Synonyms: AAG13; Aging-associated gene 13 protein; aging-associated protein 13; DT1P1A7; MGC17528; Protein S100-A16; Protein S100-F; S100 calcium binding protein A16; S100 calcium-binding protein A16; S100A16; S100F; S10AG
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Gene Symbols: S100A16
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Molecular weight:
11,801 Da
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Basal Isoelectric point:
6.28
Predict pI for various phosphorylation states
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