SYAP1 Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation. Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas (PubMed:23300339). Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: Xp22.2
Cellular Component:  axon; cell junction; cytosol; dendrite; extrinsic component of cytoplasmic side of plasma membrane; Golgi apparatus; growth cone; nucleoplasm; perikaryon; perinuclear region of cytoplasm; postsynaptic membrane; presynaptic membrane
Molecular Function:  protein binding
Biological Process:  cell differentiation; cellular response to epidermal growth factor stimulus; cellular response to insulin stimulus; cellular response to insulin-like growth factor stimulus; cellular response to platelet-derived growth factor stimulus; positive regulation of fat cell differentiation; positive regulation of protein homodimerization activity; positive regulation of protein serine/threonine kinase activity; TORC2 signaling
Reference #:  Q96A49 (UniProtKB)
Alt. Names/Synonyms: BSD domain-containing signal transducer and Akt interactor protein; BSTA; DKFZp686K221; FLJ14495; FLJ44185; PRO3113; SAP47 homolog; SYAP1; synapse associated protein 1; synapse associated protein 1, SAP47 homolog; synapse associated protein 1, SAP47 homolog (Drosophila); Synapse-associated protein 1
Gene Symbols: SYAP1
Molecular weight: 39,933 Da
Basal Isoelectric point: 4.45  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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SYAP1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene