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envoplakin
Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. Belongs to the plakin or cytolinker family. Exclusively expressed in stratified squamous epithelia. Note: This description may include information from UniProtKB.
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| Protein type: Adaptor/scaffold |
| Chromosomal Location of human Ortholog: 17q25.1 |
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Cellular Component:
cornified envelope; cytoplasm; cytosol; desmosome; intermediate filament; intermediate filament cytoskeleton; membrane
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Molecular Function:
structural molecule activity
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Biological Process:
epidermis development; intermediate filament cytoskeleton organization; keratinization; keratinocyte differentiation; peptide cross-linking; regulation of antibacterial peptide production; wound healing
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Reference #:
Q92817
(UniProtKB)
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Alt. Names/Synonyms: 210 kDa cornified envelope precursor protein; 210 kDa paraneoplastic pemphigus antigen; Envoplakin; EVPK; EVPL; p210
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Gene Symbols: EVPL
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Molecular weight:
231,604 Da
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Basal Isoelectric point:
6.56
Predict pI for various phosphorylation states
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