TCEB3 SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 1p36.11
Cellular Component:  elongin complex; nucleoplasm
Molecular Function:  protein binding
Biological Process:  regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; transcription elongation from RNA polymerase II promoter
Reference #:  Q14241 (UniProtKB)
Alt. Names/Synonyms: EloA; ELOA1; Elongin 110 kDa subunit; elongin A; Elongin-A; FLJ38760; FLJ42849; RNA polymerase II transcription factor SIII subunit A1; SIII; SIII p110; TCEB3; TCEB3A; transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A); transcription elongation factor B alpha subunit; Transcription elongation factor B polypeptide 3
Gene Symbols: ELOA
Molecular weight: 89,909 Da
Basal Isoelectric point: 9.59  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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TCEB3

Protein Structure Not Found.


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