|
TCEB3
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). Note: This description may include information from UniProtKB.
|
| Protein type: DNA-binding; Transcription factor |
| Chromosomal Location of human Ortholog: 1p36.11 |
|
Cellular Component:
elongin complex; nucleoplasm; site of DNA damage
|
|
Molecular Function:
protein binding
|
|
Biological Process:
regulation of transcription by RNA polymerase II; transcription elongation by RNA polymerase II; transcription initiation at RNA polymerase II promoter
|
|
Reference #:
Q14241
(UniProtKB)
|
|
Alt. Names/Synonyms: EloA; ELOA1; Elongin 110 kDa subunit; elongin A; Elongin-A; FLJ38760; FLJ42849; RNA polymerase II transcription factor SIII subunit A1; SIII; SIII p110; TCEB3; TCEB3A; transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A); transcription elongation factor B alpha subunit; Transcription elongation factor B polypeptide 3; transcription elongation factor B subunit 3
|
|
Gene Symbols: ELOA
|
|
Molecular weight:
87,230 Da
|
|
Basal Isoelectric point:
9.59
Predict pI for various phosphorylation states
|
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
|
