PPIG PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing. Ubiquitous. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cyclophilin; EC; Isomerase
Chromosomal Location of Human Ortholog: 2q31.1
Cellular Component:  cytosol; nuclear matrix; nuclear speck; nucleoplasm; nucleus
Molecular Function:  cyclosporin A binding; peptidyl-prolyl cis-trans isomerase activity; protein binding
Biological Process:  protein peptidyl-prolyl isomerization; RNA splicing
Reference #:  Q13427 (UniProtKB)
Alt. Names/Synonyms: CARS-cyclophilin; CARS-Cyp; CASP10; Clk-associating RS-cyclophilin; Cyclophilin G; CYP; MGC133241; Peptidyl-prolyl cis-trans isomerase G; Peptidyl-prolyl isomerase G; peptidyl-prolyl isomerase G (cyclophilin G); peptidylprolyl isomerase G (cyclophilin G); PPIase G; PPIG; Rotamase G; SR-cyclophilin; SR-cyp; SRcyp
Gene Symbols: PPIG
Molecular weight: 88,617 Da
Basal Isoelectric point: 10.29  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein