SFRS9 Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10. Belongs to the splicing factor SR family. Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle. Note: This description may include information from UniProtKB.
Protein type: RNA splicing; RNA-binding; Spliceosome
Chromosomal Location of human Ortholog: 12q24.31
Cellular Component:  nuclear speck; nucleolus; nucleoplasm
Molecular Function:  protein binding; protein domain specific binding; RNA binding
Biological Process:  alternative mRNA splicing, via spliceosome; mRNA processing; mRNA splice site selection; mRNA splicing, via spliceosome; negative regulation of mRNA splicing, via spliceosome; response to alkaloid; response to toxic substance
Reference #:  Q13242 (UniProtKB)
Alt. Names/Synonyms: Pre-mRNA-splicing factor SRp30C; serine and arginine rich splicing factor 9; Serine/arginine-rich splicing factor 9; SFRS9; Splicing factor, arginine/serine-rich 9; SR splicing factor 9; SRP30C; SRSF9
Gene Symbols: SRSF9
Molecular weight: 25,542 Da
Basal Isoelectric point: 8.74  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene