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SFRS9
Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10. Belongs to the splicing factor SR family. Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle. Note: This description may include information from UniProtKB.
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| Protein type: RNA splicing; RNA-binding; Spliceosome |
| Chromosomal Location of human Ortholog: 12q24.31 |
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Cellular Component:
nuclear speck; nucleolus; nucleoplasm
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Molecular Function:
protein binding; protein domain specific binding; RNA binding
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Biological Process:
alternative mRNA splicing, via spliceosome; mRNA processing; mRNA splice site selection; mRNA splicing, via spliceosome; negative regulation of mRNA splicing, via spliceosome; response to alkaloid; response to toxic substance
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Reference #:
Q13242
(UniProtKB)
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Alt. Names/Synonyms: Pre-mRNA-splicing factor SRp30C; serine and arginine rich splicing factor 9; Serine/arginine-rich splicing factor 9; SFRS9; Splicing factor, arginine/serine-rich 9; SR splicing factor 9; SRP30C; SRSF9
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Gene Symbols: SRSF9
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Molecular weight:
25,542 Da
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Basal Isoelectric point:
8.74
Predict pI for various phosphorylation states
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