SP4 Binds to GT and GC boxes promoters elements. Probable transcriptional activator. Belongs to the Sp1 C2H2-type zinc-finger protein family. Abundant in brain. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor
Chromosomal Location of human Ortholog: 7p15.3
Cellular Component:  cytosol; nucleoplasm
Molecular Function:  DNA-binding transcription factor activity, RNA polymerase II-specific; metal ion binding; protein binding; sequence-specific DNA binding; transcription coactivator activity
Biological Process:  positive regulation of nucleic acid-templated transcription; regulation of transcription by RNA polymerase II
Reference #:  Q02446 (UniProtKB)
Alt. Names/Synonyms: HF1B; MGC130008; MGC130009; SP4; Sp4 transcription factor; SPR-1; Transcription factor Sp4
Gene Symbols: SP4
Molecular weight: 81,985 Da
Basal Isoelectric point: 6.61  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB