peregrin Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Preferentially mediates histone H3-K23 acetylation. Positively regulates the transcription of RUNX1 and RUNX2. High levels in testis. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 3p25.3
Cellular Component:  cytoplasm; cytosol; MOZ/MORF histone acetyltransferase complex; nucleoplasm; nucleus; plasma membrane
Molecular Function:  DNA binding; metal ion binding; protein binding
Biological Process:  histone H3 acetylation; histone H3-K23 acetylation; positive regulation of transcription, DNA-templated; regulation of signal transduction by p53 class mediator
Disease: Intellectual Developmental Disorder With Dysmorphic Facies And Ptosis
Reference #:  P55201 (UniProtKB)
Alt. Names/Synonyms: BR140; bromodomain and PHD finger containing 1; bromodomain and PHD finger containing, 1; Bromodomain and PHD finger-containing protein 1; bromodomain-containing protein, 140kD; BRPF1; IDDDFP; Peregrin; Protein Br140
Gene Symbols: BRPF1
Molecular weight: 137,499 Da
Basal Isoelectric point: 8.16  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein