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AF-4
Belongs to the AF4 family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Oncoprotein; Transcription factor |
| Chromosomal Location of human Ortholog: 4q21.3-q22.1 |
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Cellular Component:
super elongation complex; transcription elongation factor complex
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Molecular Function:
protein binding
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Biological Process:
regulation of gene expression
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Reference #:
P51825
(UniProtKB)
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Alt. Names/Synonyms: AF-4; AF4; AF4/FMR2 family member 1; AF4/FMR2 family, member 1; AFF1; ALL1-fused gene from chromosome 4 protein; FEL; MGC134969; MLLT2; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); PBM1; pre-B-cell monocytic leukemia partner 1; Protein AF-4; Protein FEL; Proto-oncogene AF4; translocated to, 2
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Gene Symbols: AFF1
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Molecular weight:
131,422 Da
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Basal Isoelectric point:
9.26
Predict pI for various phosphorylation states
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