AF-4 Belongs to the AF4 family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Oncoprotein; Transcription factor
Chromosomal Location of human Ortholog: 4q21.3-q22.1
Cellular Component:  transcription elongation factor complex
Molecular Function:  protein binding
Biological Process:  regulation of transcription, DNA-templated
Reference #:  P51825 (UniProtKB)
Alt. Names/Synonyms: AF-4; AF4; AF4/FMR2 family member 1; AF4/FMR2 family, member 1; AFF1; ALL1-fused gene from chromosome 4 protein; FEL; MGC134969; MLLT2; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); PBM1; pre-B-cell monocytic leukemia partner 1; Protein AF-4; Protein FEL; Proto-oncogene AF4; translocated to, 2
Gene Symbols: AFF1
Molecular weight: 131,422 Da
Basal Isoelectric point: 9.26  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene