NMT1 Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Belongs to the NMT family. Heart, gut, kidney, liver and placenta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Motility/polarity/chemotaxis; Transferase
Chromosomal Location of human Ortholog: 17q21.31
Cellular Component:  cytoplasm; cytosol; mitochondrion; plasma membrane
Molecular Function:  glycylpeptide N-tetradecanoyltransferase activity; myristoyltransferase activity; peptidyl-lysine N6-myristoyltransferase activity; protein binding
Biological Process:  cellular ketone metabolic process; in utero embryonic development; N-terminal peptidyl-glycine N-myristoylation; N-terminal protein myristoylation; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; regulation of rhodopsin mediated signaling pathway
Reference #:  P30419 (UniProtKB)
Alt. Names/Synonyms: alternative, short form NMT-S; Glycylpeptide N-tetradecanoyltransferase 1; long form, NMT-L; Myristoyl-CoA:protein N-myristoyltransferase 1; N-myristoyltransferase 1; NMT; NMT 1; NMT1; Peptide N-myristoyltransferase 1; Type I N-myristoyltransferase
Gene Symbols: NMT1
Molecular weight: 56,806 Da
Basal Isoelectric point: 7.65  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein