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JunB
Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'. Belongs to the bZIP family. Jun subfamily. Note: This description may include information from UniProtKB.
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| Protein type: Motility/polarity/chemotaxis; Oncoprotein; Transcription factor |
| Chromosomal Location of human Ortholog: 19p13.13 |
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Cellular Component:
chromatin; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex; transcription factor AP-1 complex; transcription regulator complex
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Molecular Function:
DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific double-stranded DNA binding; transcription factor binding
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Biological Process:
cellular response to calcium ion; decidualization; embryonic process involved in female pregnancy; integrated stress response signaling; labyrinthine layer blood vessel development; osteoblast differentiation; osteoblast proliferation; osteoclast differentiation; osteoclast proliferation; positive regulation of cell differentiation; positive regulation of transcription by RNA polymerase II; regulation of cell cycle; regulation of cell population proliferation; regulation of T-helper 17 cell differentiation; regulation of transcription by RNA polymerase II; trophectodermal cell differentiation; vasculogenesis
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Reference #:
P17275
(UniProtKB)
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Alt. Names/Synonyms: activator protein 1; AP-1; jun B proto-oncogene; JUNB; JunB proto-oncogene, AP-1 transcription factor subunit; Transcription factor jun-B
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Gene Symbols: JUNB
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Molecular weight:
35,879 Da
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Basal Isoelectric point:
9.27
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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