ZFX
Probable transcriptional activator. Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: C2H2-type zinc finger protein |
Chromosomal Location of human Ortholog: Xp22.11 |
Cellular Component:
chromatin; chromosome; nucleolus; nucleoplasm
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Molecular Function:
chromatin insulator sequence binding; DNA-binding transcription activator activity, RNA polymerase II-specific; metal ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding
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Biological Process:
fertilization; homeostasis of number of cells; multicellular organism growth; oocyte development; ovarian follicle development; parental behavior; positive regulation of transcription by RNA polymerase II; post-embryonic development; regulation of transcription by RNA polymerase II; spermatogenesis
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Disease: Intellectual Developmental Disorder, X-linked, Syndromic 37
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Reference #:
P17010
(UniProtKB)
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Alt. Names/Synonyms: X-linked zinc finger protein; ZFX; zinc finger protein X-linked; zinc finger protein, X-linked; Zinc finger X-chromosomal protein; ZNF926
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Gene Symbols: ZFX
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Molecular weight:
90,522 Da
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Basal Isoelectric point:
5.71
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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