ZFY
Probable transcriptional activator. Binds to the consensus sequence 5'-AGGCCY-3'. Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: C2H2-type zinc finger protein |
Chromosomal Location of human Ortholog: Yp11.2 |
Cellular Component:
chromatin; nucleolus; nucleoplasm; nucleus
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Molecular Function:
DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; metal ion binding; protein binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific DNA binding
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Biological Process:
positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II
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Reference #:
P08048
(UniProtKB)
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Alt. Names/Synonyms: MGC138710; ZFY; zinc finger protein Y-linked; zinc finger protein, Y-linked; Zinc finger Y-chromosomal protein; ZNF911
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Gene Symbols: ZFY
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Molecular weight:
90,505 Da
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Basal Isoelectric point:
5.65
Predict pI for various phosphorylation states
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