WDHD1 Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of human Ortholog: 14q22.2-q22.3
Cellular Component:  cytoplasm; nucleoplasm
Molecular Function:  DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding
Biological Process:  regulation of transcription by RNA polymerase II
Reference #:  O75717 (UniProtKB)
Alt. Names/Synonyms: Acidic nucleoplasmic DNA-binding protein 1; And-1; AND1; CHTF4; CTF4; CTF4, chromosome transmission fidelity factor 4 homolog; WD repeat and HMG-box DNA binding protein 1; WD repeat and HMG-box DNA-binding protein 1; WDHD1
Gene Symbols: WDHD1
Molecular weight: 125,967 Da
Basal Isoelectric point: 5.42  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein