eIF3-X
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis. Belongs to the CLU family. Note: This description may include information from UniProtKB.
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Protein type: Translation |
Chromosomal Location of human Ortholog: 17p13.3 |
Cellular Component:
cytoplasm
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Molecular Function:
mRNA binding
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Biological Process:
intracellular distribution of mitochondria; mitochondrion organization
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Reference #:
O75153
(UniProtKB)
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Alt. Names/Synonyms: CLU; CLU1; CLUH; clustered mitochondria (cluA/CLU1) homolog; clustered mitochondria homolog; Clustered mitochondria protein homolog; DKFZp686L05242; DKFZp686M09233; eIF3-X; FLJ23672; hypothetical protein LOC23277; K0664; KIAA0664; Protein KIAA0664
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Gene Symbols: CLUH
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Molecular weight:
146,670 Da
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Basal Isoelectric point:
5.75
Predict pI for various phosphorylation states
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CST Pathways:
Translational Control
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