eIF3-X mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis. Belongs to the CLU family. Note: This description may include information from UniProtKB.
Protein type: Translation
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component:  cytoplasm
Molecular Function:  mRNA binding
Biological Process:  intracellular distribution of mitochondria; mitochondrion organization
Reference #:  O75153 (UniProtKB)
Alt. Names/Synonyms: CLU1; Clustered mitochondria protein homolog; DKFZp686L05242; DKFZp686M09233; eIF3-X; FLJ23672; hypothetical protein LOC23277; K0664; KIAA0664; Protein KIAA0664
Gene Symbols: CLUH
Molecular weight: 146,670 Da
Basal Isoelectric point: 5.75  Predict pI for various phosphorylation states
CST Pathways:  Translational Control
Select Structure to View Below

eIF3-X

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB