PDCD5 May function in the process of apoptosis. Belongs to the PDCD5 family. Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 19q13.11
Cellular Component:  nucleus
Molecular Function:  acetyltransferase activator activity; beta-tubulin binding; DNA binding; heparin binding; protein binding
Biological Process:  apoptotic process; cellular response to transforming growth factor beta stimulus; negative regulation of cell proliferation; negative regulation of chaperone-mediated protein folding; positive regulation of apoptotic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of gene expression; positive regulation of protein import into mitochondrial outer membrane; positive regulation of release of cytochrome c from mitochondria
Reference #:  O14737 (UniProtKB)
Alt. Names/Synonyms: MGC9294; PDCD5; programmed cell death 5; Programmed cell death protein 5; Protein TFAR19; TF-1 cell apoptosis-related protein 19; TF1 cell apoptosis-related gene 19; TFAR19; TFAR19 novel apoptosis-related
Gene Symbols: PDCD5
Molecular weight: 14,285 Da
Basal Isoelectric point: 5.77  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene