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PDCD5
May function in the process of apoptosis. Belongs to the PDCD5 family. Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Apoptosis |
| Chromosomal Location of human Ortholog: 19q13.11 |
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Cellular Component:
cytosol; nucleus
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Molecular Function:
acetyltransferase activator activity; beta-tubulin binding; DNA binding; heparin binding; protein binding
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Biological Process:
apoptotic process; cellular response to transforming growth factor beta stimulus; negative regulation of cell population proliferation; negative regulation of chaperone-mediated protein folding; positive regulation of apoptotic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of gene expression; positive regulation of protein insertion into mitochondrial outer membrane; positive regulation of release of cytochrome c from mitochondria
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Reference #:
O14737
(UniProtKB)
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Alt. Names/Synonyms: MGC9294; PDCD5; programmed cell death 5; Programmed cell death protein 5; Protein TFAR19; TF-1 cell apoptosis-related protein 19; TF1 cell apoptosis-related gene 19; TFAR19; TFAR19 novel apoptosis-related
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Gene Symbols: PDCD5
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Molecular weight:
14,285 Da
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Basal Isoelectric point:
5.77
Predict pI for various phosphorylation states
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