IRX2 Belongs to the TALE/IRO homeobox family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 13 C1|13 39.23 cM
Cellular Component:  nucleus
Molecular Function:  DNA binding; sequence-specific DNA binding
Biological Process:  metanephros development; negative regulation of transcription by RNA polymerase II; proximal/distal pattern formation involved in metanephric nephron development; regulation of transcription, DNA-templated; specification of loop of Henle identity
Reference #:  P81066 (UniProtKB)
Alt. Names/Synonyms: Homeodomain protein IRXA2; Iroquois homeobox 2; Iroquois homeobox protein 2; Iroquois related homeobox 2; Iroquois related homeobox 2 (Drosophila); Iroquois-class homeobox protein Irx6; Iroquois-class homeodomain protein IRX-2; Irx2; Irx6; Irxa2; MGC103290
Gene Symbols: Irx2
Molecular weight: 49,484 Da
Basal Isoelectric point: 5.1  Predict pI for various phosphorylation states
Select Structure to View Below

IRX2

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene