calponin 3 Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family. Expressed in both non-smooth muscle tissues as well as smooth muscle tissues. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q41
Cellular Component:  actin cytoskeleton; actin filament; cytosol; dendrite; dendritic spine; microtubule; neuronal cell body; postsynaptic density
Molecular Function:  actin binding; calmodulin binding; microtubule binding; protein binding, bridging
Biological Process:  actomyosin structure organization; epithelial cell differentiation; negative regulation of ATPase activity
Reference #:  P37397 (UniProtKB)
Alt. Names/Synonyms: acidic calponin; calponin 3, acidic; Calponin, acidic isoform; Calponin, non-muscle isoform; Calponin-3; Cnn3
Gene Symbols: Cnn3
Molecular weight: 36,435 Da
Basal Isoelectric point: 5.47  Predict pI for various phosphorylation states
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calponin 3

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene