CAP1
Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. Belongs to the CAP family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Actin-binding; Cytoskeletal |
Chromosomal Location of human Ortholog: 1p34.2 |
Cellular Component:
azurophil granule lumen; cortical actin cytoskeleton; cytoplasm; extracellular region; plasma membrane
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Molecular Function:
actin binding; adenylate cyclase binding; protein binding
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Biological Process:
actin filament organization; activation of adenylate cyclase activity; ameboidal-type cell migration; cAMP-mediated signaling; cell morphogenesis; establishment or maintenance of cell polarity; receptor-mediated endocytosis; signal transduction
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Reference #:
Q01518
(UniProtKB)
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Alt. Names/Synonyms: adenylate cyclase associated protein 1; Adenylyl cyclase-associated protein 1; CAP; CAP 1; CAP, adenylate cyclase-associated protein 1; CAP, adenylate cyclase-associated protein 1 (yeast); CAP1; CAP1-PEN; cyclase associated actin cytoskeleton regulatory protein 1; testis secretory sperm-binding protein Li 218p
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Gene Symbols: CAP1
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Molecular weight:
51,901 Da
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Basal Isoelectric point:
8.24
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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