CAP1 Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. Belongs to the CAP family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Actin-binding; Cytoskeletal
Chromosomal Location of human Ortholog: 1p34.2
Cellular Component:  azurophil granule lumen; cortical actin cytoskeleton; cytoplasm; extracellular region; plasma membrane
Molecular Function:  actin binding; adenylate cyclase binding; protein binding
Biological Process:  actin filament organization; activation of adenylate cyclase activity; ameboidal-type cell migration; cAMP-mediated signaling; cell morphogenesis; establishment or maintenance of cell polarity; receptor-mediated endocytosis; signal transduction
Reference #:  Q01518 (UniProtKB)
Alt. Names/Synonyms: adenylate cyclase associated protein 1; Adenylyl cyclase-associated protein 1; CAP; CAP 1; CAP, adenylate cyclase-associated protein 1; CAP, adenylate cyclase-associated protein 1 (yeast); CAP1; CAP1-PEN; cyclase associated actin cytoskeleton regulatory protein 1; testis secretory sperm-binding protein Li 218p
Gene Symbols: CAP1
Molecular weight: 51,901 Da
Basal Isoelectric point: 8.24  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein