ZDHHC5
Palmitoyl acyltransferase for the G-protein coupled receptor SSTR5. Also palmitoylates FLOT2. Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: EC 2.3.1.225; Membrane protein, integral; Membrane protein, multi-pass; Transferase |
Chromosomal Location of mouse Ortholog: 2|2 D |
Cellular Component:
cell surface; dendrite; GABA-ergic synapse; glutamatergic synapse; membrane; nucleoplasm; phagocytic vesicle; plasma membrane; postsynaptic specialization, intracellular component
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Molecular Function:
acyltransferase activity; palmitoyltransferase activity; protein binding; protein-cysteine S-palmitoyltransferase activity; transferase activity
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Biological Process:
immune system process; innate immune response; lipid transport; positive regulation of pattern recognition receptor signaling pathway; positive regulation of protein localization to phagocytic vesicle; positive regulation of protein localization to plasma membrane; protein localization to plasma membrane; protein palmitoylation; regulation of postsynaptic membrane neurotransmitter receptor levels
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Reference #:
Q8VDZ4
(UniProtKB)
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Alt. Names/Synonyms: 1110032A17Rik; AI451382; DHHC-5; Kiaa1748; MGC28179; OTTMUSP00000014518; Palmitoyltransferase ZDHHC5; Probable palmitoyltransferase ZDHHC5; ZDHC5; Zdhhc5; Zinc finger DHHC domain-containing protein 5; zinc finger, DHHC domain containing 5; Zisp
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Gene Symbols: Zdhhc5
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Molecular weight:
77,501 Da
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Basal Isoelectric point:
9.17
Predict pI for various phosphorylation states
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