ZDHHC5 Palmitoyl acyltransferase for the G-protein coupled receptor SSTR5. Also palmitoylates FLOT2. Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 2.3.1.225; Membrane protein, integral; Membrane protein, multi-pass; Transferase
Chromosomal Location of mouse Ortholog: 2|2 D
Cellular Component:  cell surface; dendrite; GABA-ergic synapse; glutamatergic synapse; membrane; nucleoplasm; phagocytic vesicle; plasma membrane; postsynaptic specialization, intracellular component
Molecular Function:  acyltransferase activity; palmitoyltransferase activity; protein binding; protein-cysteine S-palmitoyltransferase activity; transferase activity
Biological Process:  immune system process; innate immune response; lipid transport; positive regulation of pattern recognition receptor signaling pathway; positive regulation of protein localization to phagocytic vesicle; positive regulation of protein localization to plasma membrane; protein localization to plasma membrane; protein palmitoylation; regulation of postsynaptic membrane neurotransmitter receptor levels
Reference #:  Q8VDZ4 (UniProtKB)
Alt. Names/Synonyms: 1110032A17Rik; AI451382; DHHC-5; Kiaa1748; MGC28179; OTTMUSP00000014518; Palmitoyltransferase ZDHHC5; Probable palmitoyltransferase ZDHHC5; ZDHC5; Zdhhc5; Zinc finger DHHC domain-containing protein 5; zinc finger, DHHC domain containing 5; Zisp
Gene Symbols: Zdhhc5
Molecular weight: 77,501 Da
Basal Isoelectric point: 9.17  Predict pI for various phosphorylation states
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ZDHHC5

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene