RAB11FIP5 Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis. Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of mouse Ortholog: 6 C3|6 37.35 cM
Cellular Component:  centriolar satellite; cytoplasm; cytoplasmic vesicle; early endosome; endosome; Golgi apparatus; intracellular membrane-bounded organelle; membrane; mitochondrial outer membrane; mitochondrion; phagocytic vesicle; recycling endosome; secretory granule
Molecular Function:  gamma-tubulin binding; small GTPase binding
Biological Process:  cellular response to acidic pH; cellular response to type II interferon; insulin secretion involved in cellular response to glucose stimulus; negative regulation of adiponectin secretion; protein transport; regulated exocytosis; regulation of protein localization to cell surface
Reference #:  Q8R361 (UniProtKB)
Alt. Names/Synonyms: 9130206P09Rik; C75969; D6Ertd32; D6Ertd32e; GAF; GAF1; mKIAA0857; RAB11 family interacting protein 5 (class I); Rab11 family-interacting protein 5; Rab11-FIP5; Rab11-interacting protein Rip11; Rab11fip5; RFIP5; Rip11
Gene Symbols: Rab11fip5
Molecular weight: 69,553 Da
Basal Isoelectric point: 9.17  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein