PABP 4 Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Belongs to the polyadenylate-binding protein type-1 family. Expressed at low levels in resting normal T cells; following T-cell activation, however, mRNA levels are rapidly up-regulated. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: RNA-binding; Translation
Chromosomal Location of Human Ortholog: 4|4 D2.2
Cellular Component:  cytoplasm; cytoplasmic stress granule; cytosol; nucleus; ribonucleoprotein complex
Molecular Function:  mRNA 3'-UTR binding; mRNA binding; poly(A) binding; poly(U) RNA binding; RNA binding
Biological Process:  myeloid cell development; regulation of mRNA stability
Reference #:  Q6PHQ9 (UniProtKB)
Alt. Names/Synonyms: MCG5546, isoform CRA_c; MGC11665; MGC6685; OTTMUSP00000009342; OTTMUSP00000009343; PABP; PABP 4; Pabpc4; Poly A binding protein, cytoplasmic 4; Poly(A) binding protein, cytoplasmic 4; Polyadenylate-binding protein; polyadenylate-binding protein 4
Gene Symbols: Pabpc4
Molecular weight: 72,242 Da
Basal Isoelectric point: 9.43  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene