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LARP4
RNA binding protein that binds to the poly-A tract of mRNA molecules. Associates with the 40S ribosomal subunit and with polysomes. Plays a role in the regulation of mRNA translation. Plays a role in the regulation of cell morphology and cytoskeletal organization. 7 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: RNA-binding |
| Chromosomal Location of mouse Ortholog: 15|15 F1 |
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Cellular Component:
cytoplasm; cytoplasmic stress granule; cytosol; cytosolic small ribosomal subunit; polysome
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Molecular Function:
mRNA 3'-UTR binding; nucleic acid binding; poly(A) binding; RNA binding
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Biological Process:
cytoskeleton organization; positive regulation of translation; post-transcriptional regulation of gene expression; regulation of cell morphogenesis; translation
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Reference #:
Q8BWW4
(UniProtKB)
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Alt. Names/Synonyms: C530046N12; D330037H05Rik; DXErtd793; DXErtd793e; La ribonucleoprotein domain family member 4; La ribonucleoprotein domain family, member 4; La-related protein 4; Larp4
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Gene Symbols: Larp4
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Molecular weight:
79,763 Da
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Basal Isoelectric point:
6.02
Predict pI for various phosphorylation states
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