INPP4 Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-bisphosphate. Belongs to the inositol 3,4-bisphosphate 4-phosphatase family. Isoform 1 is expressed in the platelets, MEG-01 megakaryocytes and Jurkat T-cells. Isoform 2 is expressed in the brain. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - inositol phosphate; EC; Phosphatase, lipid
Chromosomal Location of Human Ortholog: 1 B|1 15.46 cM
Cellular Component:  cytoplasm
Molecular Function:  hydrolase activity; phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity; phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
Biological Process:  polyphosphate catabolic process
Reference #:  Q9EPW0 (UniProtKB)
Alt. Names/Synonyms: 107kDa; 9630012D15; D130048C09Rik; Inositol polyphosphate 4-phosphatase type I; inositol polyphosphate-4-phosphatase, type I; INP4A; Inpp4a; R74740; Type I inositol 3,4-bisphosphate 4-phosphatase; Type I inositol-3,4-bisphosphate 4-phosphatase
Gene Symbols: Inpp4a
Molecular weight: 105,540 Da
Basal Isoelectric point: 6.64  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene