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FABP4
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Note: This description may include information from UniProtKB.
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| Protein type: Lipid-binding |
| Chromosomal Location of rat Ortholog: 2q23 |
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Cellular Component:
cytoplasm; cytosol; lipid droplet; nucleus
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Molecular Function:
fatty acid binding; hormone receptor binding; lipid binding; long-chain fatty acid binding; long-chain fatty acid transporter activity; protein binding
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Biological Process:
brown fat cell differentiation; cellular response to lithium ion; cellular response to tumor necrosis factor; cholesterol homeostasis; fatty acid metabolic process; fatty acid transport; long-chain fatty acid transport; negative regulation of DNA-templated transcription; negative regulation of protein kinase activity; positive regulation of cell population proliferation; positive regulation of cold-induced thermogenesis; positive regulation of fat cell proliferation; positive regulation of inflammatory response; response to bacterium; response to glucocorticoid; response to gravity; response to xenobiotic stimulus; white fat cell differentiation
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Reference #:
P70623
(UniProtKB)
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Alt. Names/Synonyms: A-FABP; Adipocyte lipid-binding protein; Adipocyte-type fatty acid-binding protein; AFABP; ALBP; aP2; Fabp4; fatty acid binding protein 4, adipocyte; Fatty acid-binding protein 4; Fatty acid-binding protein, adipocyte
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Gene Symbols: Fabp4
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Molecular weight:
14,708 Da
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Basal Isoelectric point:
7.72
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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