K7 Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family. Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of rat Ortholog: 7q36
Cellular Component:  cytoplasm; cytosol; intermediate filament cytoskeleton; keratin filament
Molecular Function:  structural constituent of skin epidermis
Biological Process:  intermediate filament organization; keratinization
Reference #:  Q6IG12 (UniProtKB)
Alt. Names/Synonyms: CK-7; Cytokeratin-7; K2C7; K7; Kb7; keratin 7; keratin complex 2, basic, gene 7; Keratin, type II cytoskeletal 7; Keratin-7; Krt2-7; Krt7; type II keratin Kb7; Type-II keratin Kb7
Gene Symbols: Krt7
Molecular weight: 50,709 Da
Basal Isoelectric point: 5.67  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene