GADS Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc. Belongs to the GRB2/sem-5/DRK family. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 15|15 E1
Cellular Component:  cytoplasm; endosome; nucleus
Molecular Function:  protein binding
Reference #:  O89100 (UniProtKB)
Alt. Names/Synonyms: Adapter protein GRID; Gads; GADS protein; GRAP-2; Grap2; GRB-2-like protein; GRB-2-related monocytic adapter protein; Grb2-related adaptor downstream of Sch; GRB2-related adaptor protein 2; GRB2L; GRBLG; GrbX; Grf40; Grid; Growth factor receptor-binding protein; GrpL; Hematopoietic cell-associated adaptor protein GrpL; MONA; Monocytic adapter; monocytic adaptor; P38
Gene Symbols: Grap2
Molecular weight: 36,810 Da
Basal Isoelectric point: 6.1  Predict pI for various phosphorylation states
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GADS

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene