GADS
Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc. Belongs to the GRB2/sem-5/DRK family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Adaptor/scaffold |
Chromosomal Location of mouse Ortholog: 15|15 E1 |
Cellular Component:
cytoplasm; cytosol; endosome; nucleoplasm; nucleus; plasma membrane
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Molecular Function:
phosphotyrosine residue binding; protein binding
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Biological Process:
regulation of MAPK cascade; signal transduction
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Reference #:
O89100
(UniProtKB)
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Alt. Names/Synonyms: Adapter protein GRID; Gads; GADS protein; GRA; GRAP-2; Grap2; GRB; GRB-2-like protein; GRB-2-related monocytic adapter protein; Grb2-related adaptor downstream of Sch; GRB2-related adaptor protein 2; GRB2L; GRBLG; GrbX; Grf4; Grf40; Grid; Growth factor receptor-binding protein; GrpL; Hematopoietic cell-associated adaptor protein GrpL; MONA; Monocytic adapter; monocytic adaptor; P38
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Gene Symbols: Grap2
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Molecular weight:
36,810 Da
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Basal Isoelectric point:
6.1
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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