GOLGA5 a member of the golgin family of proteins, whose members localize to the Golgi. Involved in regulating the architecture of the Golgi apparatus. A coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues. Highly phosphorylated during mitosis. Phosphorylation is barely detectable during interphase. Two splice variant isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12|12 E
Cellular Component:  cis-Golgi network; COPI-coated vesicle membrane; Golgi apparatus; Golgi cis cisterna; Golgi cisterna; Golgi medial cisterna; Golgi membrane; Golgi trans cisterna; integral component of membrane; membrane
Molecular Function:  protein binding; protein binding, bridging; protein homodimerization activity; Rab GTPase binding
Biological Process:  Golgi organization; Golgi vesicle transport; retrograde transport, vesicle recycling within Golgi
Reference #:  Q9QYE6 (UniProtKB)
Alt. Names/Synonyms: GOGA5; Golga5; golgi autoantigen, golgin subfamily a, 5; Golgin subfamily A member 5; Golgin-84; MGC102087; Protein Ret-II; Protein Sumiko; Ret-II; Retii
Gene Symbols: Golga5
Molecular weight: 82,368 Da
Basal Isoelectric point: 5.89  Predict pI for various phosphorylation states
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GOLGA5

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene