En-2 Belongs to the engrailed homeobox family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 7q36.3
Cellular Component:  fibrillar center; membrane; nucleolus; nucleus
Molecular Function:  DNA-binding transcription factor activity, RNA polymerase II-specific
Biological Process:  embryonic brain development; hindbrain development; midbrain development; multicellular organism development; negative regulation of neuron apoptotic process; neuron development; positive regulation of transcription by RNA polymerase II
Disease: Autism, Susceptibility To, 10
Reference #:  P19622 (UniProtKB)
Alt. Names/Synonyms: En-2; EN2; engrailed homeobox 2; engrailed homolog 2; engrailed-2; HME2; Homeobox protein en-2; Homeobox protein engrailed-2; Hu-En-2
Gene Symbols: EN2
Molecular weight: 34,211 Da
Basal Isoelectric point: 9.49  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene