En-2 Belongs to the engrailed homeobox family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 5 B1|5 13.94 cM
Cellular Component:  fibrillar center; membrane; nucleolus; nucleus; RSC-type complex
Molecular Function:  DNA binding; sequence-specific DNA binding
Biological Process:  dopaminergic neuron differentiation; embryonic brain development; hindbrain development; midbrain development; multicellular organism development; negative regulation of neuron apoptotic process; neuron development; neuron differentiation; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated
Reference #:  P09066 (UniProtKB)
Alt. Names/Synonyms: BB131122; En-2; En2; engrailed 2; HME2; Homeobox protein en-2; Homeobox protein engrailed-2; Mo-En-2
Gene Symbols: En2
Molecular weight: 33,817 Da
Basal Isoelectric point: 9.47  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene