ataxin-2L
Involved in the regulation of stress granule and P-body formation. Belongs to the ataxin-2 family. Expressed at high levels in thymus, lymph node, spleen, fetal kidney and adult testis. Constitutively associated with MPL and EPOR in hematopoietic cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Membrane protein, peripheral; RNA-binding |
Chromosomal Location of mouse Ortholog: 7|7 F3 |
Cellular Component:
cytoplasm; cytoplasmic stress granule; cytosol; membrane; nuclear speck; nucleus
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Molecular Function:
mRNA binding; RNA binding
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Biological Process:
mRNA metabolic process; stress granule assembly
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Reference #:
Q7TQH0
(UniProtKB)
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Alt. Names/Synonyms: A2D; A2LG; A2lp; A2RP; ataxin 2 related protein; ataxin 2-like; Ataxin-2-like protein; ataxin-2L; ATX2L; Atxn2l; Atxnl2
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Gene Symbols: Atxn2l
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Molecular weight:
110,649 Da
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Basal Isoelectric point:
8.94
Predict pI for various phosphorylation states
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