USP24 Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron. Belongs to the peptidase C19 family. Note: This description may include information from UniProtKB.
Protein type: EC 3.4.19.12; Protease; Ubiquitin-specific protease
Chromosomal Location of Human Ortholog: 1p32.3
Cellular Component:  nucleoplasm
Molecular Function:  thiol-dependent ubiquitinyl hydrolase activity
Biological Process:  protein deubiquitination; ubiquitin-dependent protein catabolic process
Reference #:  Q9UPU5 (UniProtKB)
Alt. Names/Synonyms: Deubiquitinating enzyme 24; FLJ31309; KIAA1057; Ubiquitin carboxyl-terminal hydrolase 24; ubiquitin specific peptidase 24; ubiquitin specific protease 24; Ubiquitin thioesterase 24; ubiquitin thiolesterase 24; ubiquitin-specific processing protease 24; Ubiquitin-specific-processing protease 24; UBP24; USP24
Gene Symbols: USP24
Molecular weight: 294,365 Da
Basal Isoelectric point: 5.79  Predict pI for various phosphorylation states
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USP24

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene