ZDHHC8 Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1. Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Membrane protein, integral; Membrane protein, multi-pass; Transferase
Chromosomal Location of Human Ortholog: 22q11.21
Cellular Component:  cytoplasmic vesicle membrane; cytosol; Golgi apparatus; integral component of membrane; mitochondrion
Molecular Function:  palmitoyltransferase activity; protein-cysteine S-palmitoyltransferase activity
Biological Process:  high-density lipoprotein particle assembly; locomotory behavior; protein palmitoylation
Reference #:  Q9ULC8 (UniProtKB)
Alt. Names/Synonyms: DHHC-8; DHHC8; KIAA1292; membrane-associated DHHC8 zinc finger protein; Palmitoyltransferase ZDHHC8; Probable palmitoyltransferase ZDHHC8; ZDHC8; ZDHHC8; ZDHHCL1; Zinc finger DHHC domain-containing protein 8; zinc finger DHHC-type containing 8; zinc finger DHHC-type palmitoyltransferase 8; Zinc finger protein 378; zinc finger, DHHC domain containing 8; zinc finger, DHHC domain like containing 1; zinc finger, DHHC-type containing 8; ZNF378
Gene Symbols: ZDHHC8
Molecular weight: 81,443 Da
Basal Isoelectric point: 9.33  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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