CKB Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - arginine and proline; EC; Kinase, other
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component:  cytosol; dendrite; extracellular space; neuronal cell body; nucleus
Molecular Function:  ATP binding; creatine kinase activity; protein binding; ubiquitin protein ligase binding
Biological Process:  cellular chloride ion homeostasis; cerebellum development; creatine metabolic process; phosphorylation
Reference #:  P12277 (UniProtKB)
Alt. Names/Synonyms: B-CK; BCK; Brain creatine kinase; CKB; CKBB; CPK-B; creatine kinase B; Creatine kinase B chain; Creatine kinase B-type; creatine kinase brain; creatine kinase brain-type; creatine kinase, brain; creatine kinase-B; Creatine phosphokinase B-type; epididymis luminal protein 211; epididymis secretory protein Li 29; HEL-211; HEL-S-29; KCRB
Gene Symbols: CKB
Molecular weight: 42,644 Da
Basal Isoelectric point: 5.34  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB