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CKB
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family. Note: This description may include information from UniProtKB.
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| Protein type: Amino Acid Metabolism - arginine and proline; EC 2.7.3.2; Kinase, other |
| Chromosomal Location of Human Ortholog: 14q32.33 |
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Cellular Component:
cytosol; dendrite; extracellular space; neuronal cell body; nucleus
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Molecular Function:
ATP binding; creatine kinase activity; protein binding; ubiquitin protein ligase binding
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Biological Process:
cellular chloride ion homeostasis; cerebellum development; creatine metabolic process; phosphorylation
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Reference #:
P12277
(UniProtKB)
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Alt. Names/Synonyms: B-CK; BCK; Brain creatine kinase; CKB; CKBB; CPK-B; creatine kinase B; Creatine kinase B chain; Creatine kinase B-type; creatine kinase brain; creatine kinase brain-type; creatine kinase, brain; creatine kinase-B; Creatine phosphokinase B-type; epididymis luminal protein 211; epididymis secretory protein Li 29; HEL-211; HEL-S-29; KCRB
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Gene Symbols: CKB
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Molecular weight:
42,644 Da
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Basal Isoelectric point:
5.34
Predict pI for various phosphorylation states
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