MGP
Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. Belongs to the osteocalcin/matrix Gla protein family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Extracellular matrix; Secreted; Secreted, signal peptide |
Chromosomal Location of mouse Ortholog: 6|6 G1 |
Cellular Component:
collagen-containing extracellular matrix; extracellular matrix; extracellular region; extracellular space; protein-containing complex
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Molecular Function:
calcium ion binding; calcium-dependent protein binding
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Biological Process:
branching morphogenesis of an epithelial tube; cartilage development; cell differentiation; lung development; multicellular organism development; ossification; protein-containing complex assembly; regulation of bone mineralization
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Reference #:
P19788
(UniProtKB)
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Alt. Names/Synonyms: matrix gamma-carboxyglutamate (gla) protein; Matrix Gla protein; Mglap; MGP
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Gene Symbols: Mgp
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Molecular weight:
12,359 Da
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Basal Isoelectric point:
9.6
Predict pI for various phosphorylation states
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