Myf-6 Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. Skeletal muscle. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of mouse Ortholog: 10 D1|10 55.96 cM
Cellular Component:  nucleus
Molecular Function:  DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; protein dimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific double-stranded DNA binding
Biological Process:  cell differentiation; multicellular organism development; muscle organ development; muscle tissue morphogenesis; negative regulation of DNA-templated transcription; positive regulation of DNA-templated transcription; positive regulation of myoblast differentiation; positive regulation of skeletal muscle fiber development; regulation of DNA-templated transcription; regulation of transcription by RNA polymerase II; skeletal muscle cell differentiation; skeletal muscle tissue development; skeletal muscle tissue regeneration; somitogenesis
Reference #:  P15375 (UniProtKB)
Alt. Names/Synonyms: bHLHc; bHLHc4; herc; Herculin; MRF; Mrf4; Muscle-specific regulatory factor 4; Myf-6; Myf6; Myogenic factor 6
Gene Symbols: Myf6
Molecular weight: 26,987 Da
Basal Isoelectric point: 5.71  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene