SRPR Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Belongs to the GTP-binding SRP family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 9|9 A4
Cellular Component:  endoplasmic reticulum; endoplasmic reticulum membrane; membrane; signal recognition particle receptor complex
Molecular Function:  GTP binding; GTPase activity; nucleotide binding; signal recognition particle binding
Biological Process:  intracellular protein transport; protein targeting; protein targeting to ER; SRP-dependent cotranslational protein targeting to membrane
Reference #:  Q9DBG7 (UniProtKB)
Alt. Names/Synonyms: 1300011P19Rik; D11Mgi2; D11Mgi27; Docking protein alpha; DP-alpha; signal recognition particle receptor ('docking protein'); Signal recognition particle receptor subunit alpha; SR-alpha; Srpr; SRPRA
Gene Symbols: Srpr
Molecular weight: 69,623 Da
Basal Isoelectric point: 9.07  Predict pI for various phosphorylation states
Select Structure to View Below

SRPR

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene